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activa bioactive logo
activa-seringues-2
Bioactive Basics
ACTIVA™ BioACTIVE™ Overview
ACTIVA™ BioACTIVE™ Research
BioACTIVE Bulk Fill
Quick Tips
PULPDENT

ACTIVA-BioACTIVE™-Cement™

Activa-Bioactive-Cement-logo

Cement – Resin/RMGI Hybrid – Dual Cure – Lute & Bond – Fluoride, Calcium & Phosphate

activa-bioactive-cement-detour
awards-test1-activa
sem-activa-2024
Physical Properties
Science of Bioactivity

The Smart Universal1 Cement

Zirconia, e.max, metal & more

ACTIVA™ BioACTIVE-CEMENT™ continuously defends your indirect restorations against microleakage2 and secondary caries.3 It is universally indicated (zirconia, e.max, metal/PFM, and more), and can be used as a luting cement in retentive preps and bonded in non-retentive preps. ACTIVA BioACTIVE-CEMENT is the superior day-to-day cement for your caries management armamentarium.

sem-activa-2024

#1 Bioactive Protection from the #1 cause of crown failures – Secondary caries caused by microleakage

Instructions for Use
Cement User Guide
Product Sheet
MSDS
ACTIVA White Paper
FAQs

1ACTIVA™ BioACTIVE-CEMENT™ is indicated for use with all zirconia, ceramic, stainless steel, and composite-based indirect restorations, except for porcelain veneers.

2Zmener O, Pameijer CH, Della Porta R. Efficacy of Bioactive Resin Composites in Sealing the Marginal Gap: An Ex Vivo Study. Scientific Archives Of Dental Sciences. 2025;7(9):48-54.

3Activa Bioactive physically seals the margin of the material and tooth interface through mineral apatite formation, subsequently protecting against microleakage, the leading cause of secondary caries and recurrent decay. Scanning electron micrographs of the Activa Bioactive-Restorative groups showed a ‘‘thicker acid-base resistant hybrid-like layer with a distinct crystallization pattern.’’ (Raghip AG, Comisi JC, Hamama HH, Mahmoud SH. In vitro elemental and micromorphological analysis of the resin-dentin interface of bioactive and bulk-fill composites. Am J Dent. 2023;36{1}:3-7.)

Smarter technologies, clinically proven to benefit you and your patients

BioACTIVE™ DEFENSE AGAINST SECONDARY CARIES

Ion-X™ ionic resin matrix helps power marginal sealing apatite crystal formation through sustained calcium, phosphate, and fluoride release & recharge, while continuously working to neutralize pH and combat acid attacks.

RESISTS STRESS, DISSIPATES FORCE

MODULUS™ patented elastomeric monomer technology is integrated into the core resin chemistry. It imparts fracture resistance through force dissipation and resists polymerization shrinkage stress, imparting greater physical stability and exceptional margins.

MOISTURE FRIENDLY WORKING DYNAMICS

A proprietary acidic phosphate monomer (M1P) and proprietary hydrophilic matrix lead to a better chemical seal while enabling successful restorations in challenging oral conditions.

KEY PROPERTIES:

Dual Cure – Universal – Moisture Tolerant – Clinically Proven – Minimized Risk of Post-op Sensitivity

Universally Versatile, Everyday Lute + Bond

ACTIVA BioACTIVE-CEMENT

clinical-procedure-activa-cement-1

Tooth is prepared to receive a crown. Note retentive crown prep.

clinical-procedure-activa-cement-2

Crown filled with ACTIVA BioACTIVE-CEMENT is seated and tack cured 1-2 seconds.

clinical-procedure-activa-cement-3

Excess cement is easily removed.

clinical-procedure-activa-cement-4

Shows finished case.

Photos courtesy of Dr. G. Franklin Shull

Dr. DiTolla and Dr. Bergeron Discuss Minimally Invasive, Bioactive Dentistry for Everyday Practices

In this video Brittany Bergeron, DDS, will critically review a variety of real-world, minimally invasive case studies using bioactive restoratives and will discuss current remineralization science, moisture friendly dental products, handling properties of “active” materials, and practical, everyday uses for bioactive cements, composites, and base/liners.

53 min
Play video

Why Do We Need Bioactive Dental Cements?

In this video we explore how ACTIVA BioACTIVE-CEMENT addresses the primary reason for failure over the long term. ACTIVA BioACTIVE-CEMENT is in Pulpdent’s line of bioactive products. Indicated for indirect applications, the cement stimulates mineral apatite formation at the material-tooth interface. This natural remineralization process knits together the restoration and the tooth, penetrates and fills micro-cracks, reduces sensitivity, guards against recurrent caries, and seals margins against microleakage and failure.

5 min
Play video

MECHANICAL PROPERTIES

STRONG & UNIVERSAL1

ACTIVA BioACTIVE-CEMENT can be bonded like a resin cement and has ionic benefits like an RMGI cement.

Shear bond strength of ACTIVA BioACTIVE-CEMENT compares favorably with leading cements and is superior to RMGI and calcium aluminate-glass ionomer cements tested.

1Use with all zirconia, ceramic, stainless steel, and composite based indirect restorations except for porcelain veneers.

ACTIVA = Bioactive Cement; RelyX = Self-adhesive Cement; FujiCEM 2 = RMGI; Ceramir = Calcium Aluminate-GI
Source: University testing38 (References: www.pulpdent.com/education-articles)

1
2

RESISTS FRACTURE

Thanks to MODULUS™ elastomeric flexion technology, ACTIVA withstands intraoral forces, flexing rather than cracking.

ACTIVA’s rubberized resin component provides unparalleled toughness and resilience. Toughness, measured by deflection at break using a 3-point bend test, is the ability of a strong, hard material to absorb stress, dissipate forces and resist fracture when a load is applied. Fatigue limit is determined by the incremental load required to cause fracture within a defined number of cycles.
Deflection at Break of ACTIVA is 2-3 times greater than composites and 5-10 times greater than GIs and RMGIs.

ACTIVA = Bioactive Cement; RelyX Unicem Automix = Self-adhesive Cement; FujiCEM 2 = RMGI; Ceramir = Calcium Aluminate-GI
Source: University testing34 (References: www.pulpdent.com/education-articles

CALCIUM, FLUORIDE & PHOSPHATE RELEASE/RECHARGE:

The following graphs show the release and recharge of calcium, phosphate and fluoride from four restorative materials. ACTIVA BioACTIVE-CEMENT (as well as the rest of the ACTIVA BioACTIVE family) display a continuous release and recharge of these essential minerals, which are naturally occurring in the saliva and are supplemented by dietary sources and release from ACTIVA. This diffusion of ions is only available in materials that can transport water. Traditional hydrophobic materials are passive and do not have the capacity for this dynamic behavior.

release-activa-graph-2024

Source: Pulpdent testing

Physical Properties

Working time at room temperature:

90 seconds

Light cure setting time:

20 seconds

Self-cure anaerobic setting time at 37°C:

≤ 5 minutes

Percentage filler by weight:

51%

Percentage reactive glass filler by weight:

19%

Fluoride release 1 day:

10.2 µg/cm²

Fluoride release 21 days (cumulative):

21.5 µg/cm²

Flexural strength:

88.4 MPa / 12,800 Psi

Compressive strength:

210 MPa / 30,500 Psi

Diametral tensile strength:

37 MPa / 5365 Psi

Film thickness:

11 microns

ACTIVA Characteristics

14217671_xl
Physical Properties
76983903_XL
Bioactive Properties
26956371_xl
Applications

Clinical Procedure

A simple cementation procedure: self-adhesive, syringe delivery, no trituration, easy clean up

clinical-procedure-activa-cement-1

Fig. 1: Tooth is prepared to receive a crown. Note retentive crown prep.

clinical-procedure-activa-cement-2

Fig. 2: Crown filled with ACTIVA BioACTIVE-CEMENT is seated and tack cured 1-2 seconds.

clinical-procedure-activa-cement-3

Fig. 3: Excess cement is easily removed

clinical-procedure-activa-cement-4

Fig. 4: Shows finished case

Photos courtesy of Dr. G. Franklin Shull

Science & Literature

activa bioactive two year clinical performance
The Dental Advisor 5 Star Clinical Performance Report
activa white paper
Click here for the ACTIVA White Paper
1

Fluoride ion release and recharge over time in three restoratives. Slowokowski L, et al. J Dent Res 93 (Spec Iss A_ 268, 2014 (iadr.org).

2

Zmener O, Pameijer CH, Hernandez S. Resistance against bacterial leakage of four luting agents used for cementation of complete cast crowns. Am J Dent 2014;27(1):51-55.

3

Zmener O, Pameijer CHH, et al. Marginal bacterial leakage in class I cavities filled with a new resin-modified glass ionomer restorative material. 2013.

4

Flexural strength and fatigue of new Activa RMGIs. Garcia-Godoy F, et al. J Dent Res 93 (Spec Iss A)_ 254, 2014 (iadr.org).

5

Deflection at break of restorative materials. University testing. Submitted for publication.

6

McCabe JF, et al. Smart Materials in Dentistry. Aust Dent J 201156 Suppl 1:3-10.

7

Cannon M, et al. Pilot study to measure fluoride ion penetration of hydrophilic sealant. AADR Annual Meeting 2010.

8

Water absorption properties of four resin-modified glass ionomer base/liner materials. (Pulpdent)

9

pH dependence on the phosphate release of Activa ionic materials. (Pulpdent)

10

Kane B, et al. Sealant adaptation and penetration into occlusal fissures. Am J Dent 2009;22(2):89-91.

11

Rusin RP, et al. Ion release from a new protective coating. AADR Annual Meeting 2011.

12

Sharma S, Kugel G, et al. Comparison of antimicrobial properties of sealants and amalgam. IADR Annual Meeting 2008. (iadr.org).

13

Naorungroj S, et al.Antibacterial surface properties of fluoride-containing resin-based sealants. J Dent 2010.

14

Prabhakar AR, et al. Comparative evaluation of the length of resin tags, viscosity and microleakage of pit and fissure sealants – an in vitro scanning electron microscope study. Contemp Clin Dent 2011;2(4):324-30.

15

Pameijer CH. Microleakage of four experimental resin modified glass ionomer restorative materials. April 2011.

16

Microleakage of dental bulk fill, conventional and self-adhesive composites. Cannavo M, et al. J Dent Res 93 (Spec Iss A) 847, 2014 (iadr.org).

17

Comparison of Mechanical Properties of Dental Restorative Material. Girn V, et al. J Dent Res 93 (Spec Iss A) 1163, 2014 (iadr.org).

18

Mechanical properties of four photo-polymerizable resin-modified base/liner materials. (Pulpdent)

19

Singla R, et al. Comparative evaluation of traditional and self-priming hydrophilic resin. J Conserv Dent 2012;15(3):233-6.

20

Water absorption and solubility of restorative materials. (Pulpdent)

21

www.nidrc.nih.gov

22

Spencer P, et al. Adhesive/dentin interface: the weak link in the composite restoration. Am Biomed Eng 2010;38(6):1989-2003.

23

Murray PE,et al. Analysis of pulpal reactions to restorative procedures, materials, pulp capping, and future therapies. Crit Rev Oral Biol Med 2002;13:509.

24

DeRouen TA, et al. Neurobehavioral effects of dental amalgam in children: a randomized clinical trial. JAMA 2006;295(15):1784-1792.

25

Nordbo H, et al. Saucer-shaped cavity preparations for posterior approximal resin composite restorations: observations up to 10 years. Quintessence Int 1998;29(1):5-11.

26

Skartveit L, et al. In vivo fluoride uptake in enamel and dentin from fluoride-containing materials. J Dent Child 1990; 57(2):97-100.

27

Wear of calcium, phosphate and fluoride releasing restorative material. University testing. Submitted for publication: IADR 2015. (iadr.org).

28

Surface roughness and wear resistance of ACTIVA compared to glass ionomers, RMGIs and flowable composites. University testing. Submitted for publication: IADR 2015. (iadr.org).

Code and Description:

activa-bioactive-cement-vc1t

VC1T – Single Pack: 5mL/7gm syringe, Translucent Shade, + 20 automix tips (15 straight black + 5 with bendable metal cannula)

activa-bioactive-cement-vc2t

VC2T – Value Pack: 2 x 5mL/7gm syringe, Translucent Shade, + 40 automix tips (30 straight black + 10 with bendable metal cannula)

activa-bioactive-cement-vc1a2

VC1A2 – Single Pack: 5mL/7gm syringe, A2 Opaque Shade, + 20 automix tips (15 straight black + 5 with bendable metal cannula)

activa-bioactive-cement-vc2a2

VC2A2 – Value Pack: 2 x 5mL/7gm syringe, A2 Opaque Shade, + 40 automix tips (30 straight black + 10 with bendable metal cannula)

a20-1

A20 – Automix Syringe Tips, Black, Pkg. 20 Use for ACTIVA and for 2.5mL, 5mL and 10mL 1:1 automix syringes

A50 – Automix Syringe Tips, Black, Pkg. 50 Use for ACTIVA and for 2.5mL, 5mL and 10mL 1:1 automix syringes

a20n1-1

A20N1 – Automix Tips, clear, with bendable 20-gauge metal cannula- pkg of 20 Use for ACTIVA and for 2.5mL, 5mL and 10mL 1:1 automix syringes

A50N1 – Automix Tips, clear, with bendable 20-gauge metal cannula- pkg of 50 Use for ACTIVA and for 2.5mL, 5mL and 10mL 1:1 automix syringes

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ACTIVA BioACTIVE – CEMENT
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